SMART
Version: A - (Academic) 
SMART A is the basic version which contains the following features: alignments, profiles, HMMs, "schnipsel" database (i.e. a blastable database of domains), basic, handmade annotations, thresholds SMART A gives a higher sensitivity/selectivity than Pfam and provides some annotation. System requirements: unix Software/DB requirements (public domain tools held locally): HMMER2, searchwise, blast, (SWISSPROT DB in house recommended) Knowledge requirement: for installation and usage of publicly available search software (see above)
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